Cold Spring Harbor Laboratory
Genes Can Be Turned On and Off
Regulations exist in many places from business to schools, but what about in our genes? Learn about gene regulation with an online interactive. It uses an animation to introduce the topic, many photographs of the scientists best known...
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
A Gene Is Made of DNA
Does a protein or DNA store genetic instructions for life? Follow the research from the 1920's experiments on mice through the 1940's experiments on bacteria to learn the answer to the difficult question. Scholars use an online...
Cold Spring Harbor Laboratory
Different Genes Are Active in Different Kinds of Cells
Personalized medicine prevents many trial-and-error scenarios when time counts the most. Learn how gene expression and screening genomes improves health outcomes in cancer patients, those with auto-immune disorders, and more. An online...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
One Gene Makes One Protein
Very few universities still offer a master's degree in the ecology of grasses, but that was the degree that led George Wells Beadle to an interest in genetics and later a Nobel Prize. Scholars learn about the discoveries of Dr. Beadle...
Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Cold Spring Harbor Laboratory
A Gene Is a Discrete Sequence of DNA Nucleotides
Frederick Sanger won two Nobel prizes for protein sequencing and DNA sequencing. Young scientists learn about Dr. Sanger's research and amazing discoveries. They read an article and a biography, view videos and animations, and apply...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Howard Hughes Medical Institute
Biochemistry and Cell Signaling Pathway of the Mc1r Gene
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Howard Hughes Medical Institute
Explore Your Inner Animals
Human bodies prove evolution thanks to our genes, bones, and more. Learning about specific body parts and how they evolved from other species helps individuals better understand the transition species that helped us become who we are today.
Cold Spring Harbor Laboratory
Bacteria and Viruses Have DNA Too
In the 1940s, scientists discovered bacteria conjugation, the process of DNA transfer or bacterial sex. The discovery proved that bacteria and viruses contain DNA and led to a Nobel prize. Interested individuals learn about the...
Cold Spring Harbor Laboratory
Some DNA Does Not Encode Protein
Roy John Britten easily earned a PhD in nuclear physics—but he found painting with water colors too difficult. Young scientists learn about Britten's life, career, and research with an online interactive. They read a biography, view...
Cold Spring Harbor Laboratory
Some DNA Can Jump
Some people have a natural ability to jump, but did you know DNA also naturally jumps? Learn about the fun habit by looking at the research of a pioneering female scientist. Barbara McClintock fought prejudice and surpassed her mentors...
Beyond Benign
Medical Ethics
Just because we have the ability to determine an organism's traits through genetic testing, should we do it? Middle-school medical experts examine the ethical dilemmas in biotechnology in the 18th and final installment in a series of...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Cold Spring Harbor Laboratory
Some Viruses Store Genetic Information in RNA
Can a high school program alter the entire course of your life? David Baltimore and Howard Temin participated in high school programs working in research laboratories and went on to win the 1975 Nobel Prize. Learn about these two...
Serendip
Genetic Engineering Challenge – How Can Scientists Develop a Type of Rice That Could Prevent Vitamin A Deficiency?
Brown rice contains vitamins B and E, while white rice lasts longer in storage. The availability of rice around the world makes it a great candidate for genetic engineering. Scholars apply their knowledge of genetic engineering to solve...
Cold Spring Harbor Laboratory
Higher Cells Incorporate an Ancient Chromosome
Chromosomes contain keys to history including links from royalty to Neanderthals. Young scientists learn about Ivan Wallin's research into chromosomes with an animation and videos. Then, the concept connects to mysteries related to...
Cold Spring Harbor Laboratory
Mendelian Genetics Cannot Fully Explain Human Health and Behavior
The breakthrough of Mendelian genetics solved many puzzles for biologists. Then, scientists decided to apply the theory to human behavior. Learn the story and struggle of finding a genetic explanation for hobbies, interests, and mental...
Cold Spring Harbor Laboratory
Mendelian Laws Apply to Human Beings
Why are so many inherited diseases more prevalent in populations of specified races? Scholars learn about pedigrees and genetics using a reading, an animation, primary sourced letters, a short video, a biography, a guided practice...
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