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Lesson Plan
University of Washington

Genome Sciences Education Outreach: Sickle Cell Anemia [Pdf]

For Teachers 9th - 10th
Students will use a Sickle Cell Anemia case study to learn about allele frequencies, genetics, and molecular biology.
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Handout
US National Library of Medicine

Medline Plus: Morquio Syndrome

For Students 9th - 10th
A brief, bullet-pointed explanation of the characteristics of Morquio Syndrome. The information includes symptoms, tests and treatments for the syndrome, as well as prognosis and possible complications.
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Interactive
Cold Spring Harbor Laboratory

Dolan Dna Learning Center: Disease & Mutation: Sickle Cell

For Students 9th - 10th
A brief overview of Sickle cell anemia, a genetic disease that affects hemoglobin in the blood. [1:30]
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Handout
University of Michigan

University of Michigan Health System: Your Child: Xxx Syndrome (Trisomy X)

For Students 9th - 10th
Fact page describes the genetic disorder Triple X Syndrome or Trisomy X. Includes explanation of the genetics involved as well as treatment of the disorder.
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Handout
University of Arizona

Ua: Diagnosis of Klinefelter's Syndrome

For Students 9th - 10th
Brief tutorial dealing with Klinefelter's diagnosis. Provides illustration of nondisjunction and Klinefelter's karyotype. Information provided regarding other sex chromosome aneuploidies.
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Handout
Wikimedia

Wikipedia: Klinefelter's Syndrome

For Students 9th - 10th
Wikipedia entry for Klinefelter's Syndrome in both mammals and adults. Links are also given for additional information on related subjects.
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Article
Open Curriculum

Open Curriculum: Human Inheritance

For Students 9th - 10th
This illustrated article describes the difference between a genetic trait and a genetic disease/disorder.
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Handout
Cold Spring Harbor Laboratory

Your Genes, Your Health: Down Syndrome

For Students 9th - 10th
Key facts about Down Syndrome are available on this page--just roll over the icons. For more detailed information, use the left navigation to explore causes, diagnosis, treatment, and more.
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Handout
Other

Genetica Lens: Morquio Syndrome

For Students 9th - 10th
Part of a project designed to provide visual documentation of individuals with rare genetic disorders, in order to help with the diagnosis and treatment of these disorders. This page describes Morquio Syndrome and discusses the problems...
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Website
Other

Sickle Cell Anemia Association: Sickle Cell Anemia

For Students 9th - 10th
The Sickle Cell Anemia Association invites you to "visit often to get the latest news and available information" on sickle cell anemia. Visit the FAQ section for quick facts and answers to basic questions.
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Handout
Other

Klinefelter Organisation: About Ks

For Students 9th - 10th
Excellent review of basic genetics and a description of Klinefelter's Syndrome.
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Handout
Science Daily

Science Daily: Iowa Researchers Rare, Accelerated Aging Condition

For Students 9th - 10th
Article summarizes recent University of Iowa research. Progeria patients show deficiencies in certain antioxidant enzymes. Author provides information about possible application of gene therapy in future progeria research and treatment
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Graphic
National Health Museum

Access Excellence: Inheritance of Hemophilia

For Students 9th - 10th
This site explains the X-linked inheritance of Hemophilia and includes a diagram.
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Handout
National Institutes of Health

U.s. National Library of Medicine: Genetic Conditions: Huntington Disease

For Students 9th - 10th
This resource provides a summary of the disease effects on the body and the genetics behind its inheritance. There are several links to other useful sites.
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Handout
National Institutes of Health

U.s. National Library of Medicine: Genetics Home Reference: Triple X Syndrome

For Students 9th - 10th
Fact page describes Triple X Syndrome or Trisomy X. Includes explanation of the genetics involved and treatment of the disorder.
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Handout
Other

Who Named It?: Hurler's Syndrome

For Students 9th - 10th
In addition to a description of Hurler's Syndrome, this site gives biographical information about a list of people associated with the disease, including those who have done significant research.
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Website
Other

Dr. Greene's House Calls: Trisomy 13

For Students 9th - 10th
Doctor describes Trisomy 13 in layperson's terms. Explanations of chromosome 13 function, abnormalities resulting from trisomy, history of syndrome, and prenatal testing.
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Handout
WebMD

Web Md: Klinefelter's Syndrome

For Students 9th - 10th
This site from WebMD Health is a very informative approach to klinefelter's syndrome. It has a fairly in-depth topic overview, then discusses symptoms, exams, treatment, home care and other places to get help.
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Interactive
University of Utah

University of Utah: Learn Genetics: Calculating Genetic Risk

For Students 9th - 10th
How can someone estimate their chances of developing a genetic disease? Probe some of the tools used to investigate disease inheritance, and find out why it is difficult to accurately predict what family members will get certain genetic...
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Handout
WebMD

Web Md: Morquio Syndrome

For Students 9th - 10th
A brief description of Morquio Syndrome, with a list of organizations which provide support and further information.
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Handout
University of Utah

University of Utah: Learn Genetics: How Do Mutations Cause Genetic Disorders?

For Students 9th - 10th
Get a brief overview of the connection between mutations and genetic diseases. Several causes of mutations are also presented.
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Interactive
Cold Spring Harbor Laboratory

Dolan Dna Learning Center: Inheritance Calculator: Blank Make Your Own

For Students 9th - 10th
An interactive Punnett Square calculator which allows students to work out patterns of inheritance for any autosomal recessive genetic trait or disease.
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Unknown Type
Khan Academy

Khan Academy: Spherical Erythrocytes and Hemolysis

For Students 9th - 10th
Read a passage about spherical erythrocytes and hemolysis and answer the follow-up questions.
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Handout
Other

Trisomy 21: The Story of Down Syndrome

For Students 9th - 10th
Written by a physician who has a child with Down Syndrome, this article reviews basic genetics and explains the occurrence of Down Syndrome as a result of nondisjunction in cell division. Includes normal and Down karyotypes....