Curated OER
Mutations
The basics of mutation types and some potential effects of those are described and diagrammed here. Each detail is very clear and includes the labels and translation change exhibited. A great slideshow to expand on DNA replication issues.
Curated OER
Mutations
After studying DNA replication and the genetics of inheritance, this slide show is useful for explaining specific mutations that can happen and result in an illness. Sickle cell anemia, and cystic fibrosis are explained on a genetic...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
Curated OER
Translating Genetic Information
Students explore the process of translation. They determine the correct sequencing and present their strands to the class. In addition, they compare normal red blood cells to sickle cells and complete discussion questions.
Curated OER
Mutations and Genetic Change
In this genetic mutations worksheet, students compare and contrast different types of mutations including point mutations, silent mutations, and frameshift mutations. This worksheet has 5 matching, 4 fill in the blank, and 3 short answer...
Curated OER
How Is the Genetic Code Ultimately Translated Into a Protein?
Students examine the functions of mRNA, rRNA and tRNA. They explain the steps in the protein synthesis process. They practice using new vocabulary as well.
Curated OER
Construction of a Hemoglobin Gene
Students see how eight pairs of triplets are equivalent to part of a gene and control a part of heredity. They comprehend how blood corpuscles manufacture normal hemoglobin. Students already comprehend that genes control the synthesis...
Curated OER
All Aboard for Protein Synthesis
Fourth graders walk through the process of transcription and translation to demonstrate and explain protein synthesis. They utilize a worksheet imbedded in this plan to guide their role play.
Curated OER
Secret Codes
Students examine Morse code and how it is used. In this secret codes lesson students decode messages, make their own codes and have other students crack the code.
Curated OER
CONSTRUCTION OF A HEMOGLOBIN GENE
Young scholars use research to see how eight pairs of triplets are equivalent to part of a gene and control a part of heredity. They also understand how red blood corpuscles manufacture normal hemoglobin.
Curated OER
Scientist Simulation
Students imagine themselves working as research scientists completing the end-steps of a molecular research project and interpreting the data. They compare the gene sequences of normal and abnormal mice and evaluate the protein product...
Curated OER
Why Do We Need Vitamin C in Our Diet?
Students compare/contrast the DNA sequence data of the rat GULO gene to the inactive human GULO gene. They translate and align the sequences, and propose a scenario to explain the occurrence of an inactive DNA sequence to that of an...
Curated OER
Why do we need Vitamin C in our diet? Or Why do we carry old inactive genes in our genome?
Students explore and explain how mutations in the DNA sequence of a gene may be silent or result in phenotypic change in an organism and in its offspring. They analyze how evolution and biodiversity are the result of genetic changes that...
BiologyWise
Biology Wise: Codon Chart
Explains the workings of the codon translation chart which provides the keys to the structure of amino acids. Includes a widget where one can input a nucleotide triplet combination and see which amino acid it represents. Includes RNA and...
CK-12 Foundation
Ck 12: Genetic Code
[Free Registration/Login may be required to access all resource tools.] How do you go from four letters to 20 amino acids? You need a code. This module introduces the genetic code and how to read it, defines codon and reading frame, and...
University of Maryland
Univ. Of Maryland: Master of Chemical and Life Sciences: Dna Bracelets [Pdf]
Using a bead-bracelet simulation, construct a sequence of amino acids. Then, discover the effects of silent, point, and frameshift mutations.
Cold Spring Harbor Laboratory
Dna From the Beginning: Dna Words Are Three Letters Long
The genetic code is actually the three letter combination of bases that codes for an amino acid. This article describes the discovery of this code. Article includes animations, pictures, video, biographical information, and quiz...
Genome British Columbia
Genome British Columbia: Dna Code Bracelet
For this activity, students create a bracelet of beads using DNA code. Each letter represents an amino acid and is three beads. The authors suggest that even younger students would enjoy this activity, although older students will...
Khan Academy
Khan Academy: The Genetic Code
Learn how genetic code links groups of nucleotides in an mRNA to amino acids in a protein. Also learn about start codons, stop codons, and reading frame.
CK-12 Foundation
Ck 12: Translation
[Free Registration/Login may be required to access all resource tools.] Translation involves translating the language of nucleotides to the language of amino acids. During this activity, translation in protein synthesis is explored along...
Science Education Resource Center at Carleton College
Serc: Building a Protein
This hands-on activity is an assessment of the students understanding of peptide and disulfide bonds formed during protein synthesis, and the structure of an amino acid (R-group plus the common structure that all amino acids share)....
Estrella Mountain Community College
Estrella Mountain Community College: Translation
For the section including translation, go to "the genetic code" chapter in the table of contents. This explanation includes diagrams and illustrations as well as a codon code table.
CK-12 Foundation
Ck 12: Plix: Genetic Code
[Free Registration/Login Required] Synthesize a protein by dragging the amino acids to the corresponding codon on the mRNA segment. You will need a sign-in to access this interactive but it will be well worth your time!