Howard Hughes Medical Institute
Vertebrate Circulatorium
When you get to the heart of the matter, you learn a lot about an organism by studying its circulatory system! A perfect resource for a zoology or anatomy class, the simulation gives users a peek inside a variety of vertebrates to...
Howard Hughes Medical Institute
Deep History of Life on Earth
Take it all the way back! Young scientists discover the changes that took place from the time Earth became solid to present day through an interesting interactive. The resource guides users through key events that have shaped our world...
Howard Hughes Medical Institute
Visualizing Gene-Expression Patterns
How do genetics gurus know so much about gene expression? See traits materialize before your very eyes using a presentation with embedded simulations. Science scholars develop an understanding of the techniques used to follow the work of...
Howard Hughes Medical Institute
Great Transitions Interactive
How did life evolve from fish to four-limbed animals? Work through an interactive exploring transition animals and comparing their features to understand the transition. Making it even better, the interactive allows scholars to isolate...
Howard Hughes Medical Institute
Geological History of Oxygen
Earth didn't always have oxygen, so what caused the change that allows humans to live here? Learn about the change in O2 levels throughout geological history through an interactive graph. Each section offers greater detail on the changes...
Howard Hughes Medical Institute
Regulation of the Lactase Gene
All human infants are lactose tolerant, yet some adults are lactose intolerant—why is that? Individuals discover the process of gene mutation through a study of the lactase gene (LCT). They understand the geographic connections,...
Howard Hughes Medical Institute
Creating Phylogenetic Trees from DNA Sequences
How closely are animals related? Check their phylogenetic trees! The use of DNA sequencing altered our understanding of these relationships. Individuals explore and gain a better understanding of how scientists sort, align, and determine...
Biology Junction
Characteristics of Life
Life exists in many different forms from tiny nanobes to the Humongous Fungus, the largest form of life. Scholars learn the definition of life and the shared characteristics of these greatly varied organisms. They demonstrate knowledge...
Howard Hughes Medical Institute
Look Who's Coming for Dinner: Selection by Predation
What happens when a new predator comes to town? Learners analyze an experiment that studies the effect of predation on selection. They use real data to draw conclusions about the impact a new predator has on a prey species.
Howard Hughes Medical Institute
Biodiversity and Evolutionary Trees
Compare what shells look like on the outside with what makes that happen on the inside. Scholars begin by sorting an various seashells by their physical characteristics into phylogenetic trees. They then conduct a DNA comparison of...
Biology Junction
Amphibians
Biologists know of more than 2,300 living species of amphibians. Learn more about the four orders of amphibians with an interesting presentation. It explains the similarities and differences between the thousands of species of...
College Board
2018 AP® Biology Free-Response Questions
The average AP Biology score dropped in 2018 with the addition of more data tables and graphs. Offer additional practice free-response questions by using the questions from the 2018 AP exam covering phylogenetic trees, cell structure and...
Cold Spring Harbor Laboratory
Mendelian Laws Apply to Human Beings
Why are so many inherited diseases more prevalent in populations of specified races? Scholars learn about pedigrees and genetics using a reading, an animation, primary sourced letters, a short video, a biography, a guided practice...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
On the Caribbean islands, lizards expanded into different niches instead of competing for resources. Scholars discuss and learn from experts in a video how scientists prove the theory. They build phylogenetic trees based on appearances...
Howard Hughes Medical Institute
Beaks as Tools: Selective Advantage in Changing Environments
How does nature select some adaptations over others? Scholars experiment picking up seeds with two different types of tools simulating beaks. After practicing, they experience a drought where one type of seed suddenly isn't available....
Howard Hughes Medical Institute
Testing a Hypothesis
Are sickle cell disease and malaria related somehow? Scholars learn about both illnesses and the hypotheses that they are related. They discuss, view a video, and answer questions to demonstrate understanding. The resource includes an...
Cold Spring Harbor Laboratory
RNA Was the First Genetic Molecule
Can organic molecules come from a pre-biotic environment? Stanley Lloyd Miller proved it is possible when exactly the right conditions exist. Learn about his experiment and the other experiments later building off of it that changed the...
Howard Hughes Medical Institute
How Do Fibers Form?
The proteins inside a cell determine the shape of the cell. While most red blood cells have a circular shape, those with sickle cell take the shape of a sickle. This change in shape causes multiple issues in the system. Scholars solve...
Howard Hughes Medical Institute
Icefish Blood Adaptations: Viscosity
Most fish freeze to death when the water is too cold, yet some fish live in the Southern Ocean where the water is often below freezing. Scholars use two models representing the blood from most fish versus the blood from Antarctic fish....
Howard Hughes Medical Institute
Biochemistry and Cell Signaling Pathway of the Mc1r Gene
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Howard Hughes Medical Institute
Color Variation Over Time in Rock Pocket Mouse Populations
While many mutations are neutral, those that appear advantageous increase in frequency in a population. Scholars use illustrations to make predictions about populations of mice. They follow it up with a video to confirm or refute their...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Discovery Education
The Time of Our Life
Mammals are some of the newest organisms to appear on Earth. Young scholars complete an activity that results in a timeline showing the appearance of different types of living organisms. Provided with a list that spans from prokaryotes...
Howard Hughes Medical Institute
Pedigrees and the Inheritance of Lactose Intolerance
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
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