Which factor was more influential in the 1918 flu epidemic: biology, or social and political conditions? Your AP biology class will research and debate one of these positions in an interesting and challenging activity. Intended for upper-level high school or college biology courses, the reading is quite complex and may be a bit dense for a regular biology class; however, if your learners are strong readers, allowing them to think deeply about multiple aspects of an epidemic is a great way to encourage synthesis and analysis in your scholars.