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Fitzsimons (FitzSimons; Fitzsimmons) was born in Ireland in 1741. Coming to America about 1760, he pursued a mercantile career in Philadelphia. The next year, he married Catherine Meade, the daughter of a prominent local merchant, Robert Meade, and not long afterward went into business with one of his brothers-in-law. The firm of George Meade and Company soon became one of the leading commercial houses in the city and specialized in the West India trade.
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