Curated OER
DNA Fingerprinting with Gel Electrophoresis
Young scholars use DNA fingerprinting to demonstrate the concept that DNA fingerprinting can be used to identify individuals and solve problems. They use gel electrophoresis to analyze the DNA of a suspected criminal to prove innocence...
Curated OER
Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis
Students create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...
Curated OER
Genetic Engineering/Biotechnology
Students create a paper model of a plasmid and insert a DNA molecule that contains a specific gene into the plasmid. They complete an actual transformation involving E. coli bacterium and relate the two activities to one another.
Curated OER
Transcription, Translation, and the Genetics of Microbes
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
Curated OER
Cracking the Code - Cloning Paper Plasmid
Students explore the "genetic code." They observe how genes may be manipulated for genetic research, gene cloning, and genetic engineering. In a lab setting, students examine the mechanics involved in cutting and ligating DNAs into a...
Curated OER
Agarose Gel DNA Quantitation
Students examine agarose gels to compare a known DNA sample to an unknown sample to determine the quantity and size of an unknown DNA sample.
Curated OER
DNA Fingerprinting: You Be the Judge!
Learners use their knowledge of DNA fingerprinting to evaluate the use fingerprints in courts, and will address the ethics of establishing a national database of fingerprints.
Curated OER
DNA Fingerprinting: You Be the Judge!
Learners explore DNA fingerprinting. Students discover how DNA fingerprinting is done and judge the validity. They evaluate the use of certain prints in courts and address the ethics of establishing a national database of fingerprpints.
Curated OER
DNA Fingerprinting Simulation
In this DNA fingerprinting simulation worksheet, students perform an activity that represents using a gel electrophoresis. Students decide who commits a crime in a forensics style lab.
Curated OER
Wolves: DNA Pawprinting
A mystery canine was shot and killed near Yellowstone National Park in the early '90s. Genetics whizzes explain how they might go about identifying whether the animal was a true grey wolf or a hybrid. A drawing of the animal's DNA bands...
Curated OER
How is Foreign DNA Inserted into Organisms During the Genetic Engineering of Crops?
Young scholars examine the positive benefits and negative consequences of genetically modified organisms following a lecture covering key biotech concepts and techniques. Students then conduct and experiment comparing the travel rate of...
Curated OER
Lost Baby
Students simulate the steps involved in creating a DNA fingerprint by the RFLP technique. They analyze RFLP patterns to determine the parentage of a missing baby.
Curated OER
DNA Fingerprinting
Pupils experiment with chromatography as a technique which is similar to electrophoresis that scientists use to identify DNA samples.
Curated OER
DNA Extraction Laboratory Experiment
Pupils will visualize how DNA is extracted from cells by performing a simple laboratory experiment. They will then use this knowledge to further understand how scientists are using DNA extraction to try to clone human cells, and to...
Curated OER
iDNAvestigation Exploration
Students investigate DNA Fingerprinting techniques and applications. They participate in a scenario to analyze blood to discover who shattered a plexiglass backboards. In addition, they explain why the DNA fingerprint of blood from the...
TeachEngineering
Teach Engineering: Restriction Enzymes and Dna Fingerprinting
The discovery of restriction enzymes and their applications in DNA analysis has proven to be essential for biologists and chemists. This lesson focuses on restriction enzymes and their applications to DNA analysis and DNA fingerprinting....
Khan Academy
Khan Academy: Restriction Enzymes & Dna Ligase
Learn about restriction digestion, where the result has sticky ends and blunt ends. Also find out about ligation reactions.
Biology Pages
Kimball's Biology Pages: Restriction Enzymes
This site is a retired biology professor's explanation of restriction enzymes. Good visual showing examples of how enzymes cut DNA to produce blunt or sticky ends.
Other
Rebase: Restriction Enzyme Database
Searchable database of restriction enzyme information. Must have more than basic knowledge of restriction enzymes.
TeachEngineering
Teach Engineering: Dna Forensics and Color Pigments
Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint")...
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Dna Restriction
Animated slide show demonstrates the genetic engineering process of DNA restriction.
John Wiley & Sons
Interactive Concepts in Biochemistry: Restriction Digestion/gel Electrophoresis
Tutorial explains the processes of restriction digestion and gel electrophoresis and provides an interactive exercise to further your understanding.
ClassFlow
Class Flow: Gel Electrophoresis & Restriction Mapping
[Free Registration/Login Required] Following basic lab techniques of modern molecular biology, analyze the gel electrophoresis results of a restriction enzyme digest of DNA by using a HindIII-generated standard curve. Then solve two...
Annenberg Foundation
Annenberg Learner: Applied Genetic Modification
Explore practical uses of genetic engineering techniques to generate a plant that produces a hepatitis B protein for potential vaccine use. Examine the use of restriction enzymes for cloning and plasmid mapping.